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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIP1L1 All Species: 17.27
Human Site: S276 Identified Species: 47.5
UniProt: Q6UN15 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UN15 NP_001128409.1 594 66526 S276 P P S R N S T S S Q S Q T S T
Chimpanzee Pan troglodytes XP_001147016 603 67380 S276 P P S R N S T S S Q S Q T S T
Rhesus Macaque Macaca mulatta XP_001090808 594 66538 S276 P P S R N S T S S Q S Q T S T
Dog Lupus familis XP_853955 764 84414 S437 P P S R N S T S S Q S Q T S T
Cat Felis silvestris
Mouse Mus musculus Q9D824 581 64940 K270 K A S S S V G K W Q D R Y G R
Rat Rattus norvegicus Q5U317 536 60169 K241 T S P P S L F K T G L P P S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517022 711 77022 D358 P S S P R R R D P R P R L W P
Chicken Gallus gallus XP_001233386 773 84522 S445 P T N R S S A S P Q S K T S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5XJD3 570 62947 P264 N Q G R I S P P H W A G P P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 99.8 73.5 N.A. 93.5 87.7 N.A. 26.5 62.7 N.A. 53.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.5 99.8 75.9 N.A. 94.4 88.3 N.A. 37.1 68.5 N.A. 66.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 6.6 N.A. 13.3 60 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 26.6 20 N.A. 26.6 80 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 12 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 12 0 0 12 0 12 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 23 0 0 0 12 0 0 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 12 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 12 0 45 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 45 12 23 0 0 12 12 23 0 12 12 23 12 12 % P
% Gln: 0 12 0 0 0 0 0 0 0 67 0 45 0 0 0 % Q
% Arg: 0 0 0 67 12 12 12 0 0 12 0 23 0 0 23 % R
% Ser: 0 23 67 12 34 67 0 56 45 0 56 0 0 67 12 % S
% Thr: 12 12 0 0 0 0 45 0 12 0 0 0 56 0 56 % T
% Val: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 12 0 0 0 12 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _